A population based nationwide study was carried out in Finland in patients with type 1diabetes mellitus, to examine the different mortality among 10,500 patients with diabetes from an early age (0-14 years) and 6,800 others who developed diabetes later in life (15-29 years). The mean follow-up was 21 years and the study included patients from 1970 to 1999. The study reported an increase in mortality in patients who had developed diabetes at younger ages, with a mortality ratio of 3.6/year for the first group and 2.8/year for the second group, compared with the general population. The mortality from chronic complications from diabetes showed a gradual decrease with time in the early-onset group, whereas in the late-onset group this decrease was not reported. In this second group there was instead a gradual increase in mortality due to acute complications from the disease and to the use of alcohol and drugs.
(Diabetology)
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April 2012
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