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It is normal to see very variable limits in the normality range as to the values of transaminases, according to the laboratory performing the exam, and this variability often creates some problems to the patient and to the general practitioner, since an increase in this parameter could mean a liver [...]
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Since the use of statins is associated with a reduction in cholesterol production, these drugs should theoretically have a role in cholesterinic biliary lithiasis, but the trials performed up to now have only given inconclusive results. Now, some researchers in England have used a registry of [...]
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Paracetamol-induced liver toxicity (both following an ingestion of high doses and for very-long-term therapies) is the commonest cause of acute liver failure in the USA, so researchers have wondered on the problem of the safety of analgesics and OTC NSAIDs. In order to better evaluate their [...]
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Non-alcoholic fatty liver is more and more increasing and not only as a histological curiosity, but also as a clinical condition implying even serious consequences. Thiazolidinediones, approved by FDA for diabetes treatment, improve liver histology in diabetic patients, so researchers have thought [...]
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In patients affected by chronic hepatitis B, one generally decides the execution of a liver biopsy and a possible treatment according to liver enzyme levels. But there are some uncertainties on the progression of the disease in patients presenting normal levels of liver enzymes. A trial was [...]
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The discovery of altered liver enzymes is very frequent, but its interpretation often puts the general practitioner in difficulties. Some researchers have used a database of 1864 American adults who had performed liver function tests twice (averagely with an interval of 17 days): about half of them [...]
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Minimal hepatic encephalopathy (MHE) is a very mild cognitive or psycho-motor dysfunction occurring in patients affected by liver cirrhosis and presenting an apparently normal mental state. A trial was performed in India to assess the efficacy of lactulose even in this particular indication: 61 [...]
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We know that one of the worst complications of hepatitis C is represented by fibrosis onset, and that in order to make this diagnosis it is necessary a liver biopsy. To verify whether an alternative and non-invasive prediction method is possible, some researchers in Japan have examined 240 patients [...]
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Non-Alcoholic Steato-Hepatitis (NASH) is becoming more and more important as a cause for important liver dysfunction and since we know its association with resistance to insulin, it is likely to think that the drugs capable to decrease the resistance to insulin can have a beneficial effect on this [...]
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Non-alcoholic liver disease, characterized by an increase in liver enzymes without symptoms, up to little time ago, was considered a non-pathological situation, but now many authors think that this situation has its own danger. Some Swedish researchers have identified 129 consecutive patients [...]