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In the U.S. in 2009 guidelines were issued recommending the implementation of screening for celiac disease (CD) in all patients with irritable bowel syndrome, especially if diarrhea is a predominant symptom (IBS; American Journal of Gastroenterology 2009; 104 (Suppl1): S1). A prospective [...]
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Patients with chronic pancreatitis often have abdominal pain which can be difficult to control, since the available drugs are few and not very effective, not to mention the risk of addiction for patients who use narcotic analgesics. Since gabapentoids (gabapentin and pregabalin) are used in a wide [...]
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Acetylsalicylic acid and clopidogrel are used in cardiovascular prevention for their antiplatelet action, but both increase the risk of bleeding from peptic ulcers. Acetylsalicylic acid itself is a direct cause of ulcers, due to the inhibition of prostaglandin formation in the gastrointestinal [...]
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The prevalence of nonalcoholic fatty liver disease (NAFLD) and its subset, nonalcoholic steatohepatitis (NASH), varies according to the methods used to establish diagnoses and to the socio-economic situation of the population studied, these factors implying the impossibility of a generalization. [...]
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The management of reflux disease – when it becomes severe – is controversial, because a part of physicians are inclined to surgery and another one to medical therapy. In order to make a direct comparison between a PPI and anti-reflux endoscopic surgery (LARS: laparoscopic antireflux surgery) some [...]
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The association between chronic pancreatitis and alcohol intake is given for granted, but recently, new associations have been discovered that can partly change the etiology of this disease. The data from 539 patients and 695 controls (patients’ first-line relatives, partners and friends) [...]
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A study in 2010 – called COGENT – has shown that omeprazole prevents the negative gastrointestinal reactions in patients taking aspirin and clopidogrel, without increasing cardiovascular risk. In the study sample, however, only 4% of them had a positive history for peptic ulcer or gastrointestinal [...]
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In patients affected by irritable bowel syndrome, some alterations of gut flora can be found, so, in the treatment of this frequent condition, the use of antibiotics with an intestinal action has been proposed. Through the sponsorship of a pharmaceutical company, some researchers have randomized [...]
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When a patient undergoes hemorrhages or intestinal bleedings coming from terminal bowel, is it opportune to perform an urgent colonoscopy? Some researchers in California have enrolled 85 patients (averagely 52 years of age; average Hb 7.9 g/l) affected by hemodinamically significant hematochezia [...]
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With a recent cross-sectional study it was seen that the presence of large serrated polyps is an independent risk factor for colorectal synchronous cancers; according to this matter, two new studies have been performed.
The first one has involved 3121 patients undergoing screening colonoscopy in [...]