-
Patients presenting bleedings of the upper gastrointestinal tract not due to esophageal varices are treated according to international guidelines, which have been recently updated according to the available scientific evidence. The fundamental points are the following:
- Use a standardized [...]
-
When a patient under treatment with cardiologic doses of aspirin presents a peptic bleeding, he interrupts taking the drug. But is hemorrhagic risk really higher than the cardiovascular benefit obtainable with aspirin? In order to answer this question, in Hong Kong, some consecutive patients [...]
-
It is often believed that there is a correlation between the presence of an asymptomatic gastro-esophageal reflux and asthma, but a trial in 2009, based on the use of esomeprazole in patients with asthma, has disproved this conviction: the 412 examined subjects did not suffer from pyrosis (just a [...]
-
In order to obtain an acceptable weight loss in the great obese, a gastric surgery is often used, choosing between Roux-en-Y bypass and banding. These two kinds of surgery have been compared in an observational, non-randomized trial performed in California on 197 obese people. In the first 90 days, [...]
-
The role of endoscopy in the evaluation of patients with dyspepsia, above all older patients, and when to perform it are still under discussion. In order to answer the question on timing, some researchers have performed a prospective multicentric trial on 2741 patients presenting Rome-II criteria [...]
-
Since aspirin has been used in low doses in cardiologic prevention, the frequency of complications for the digestive system has been increasing and the use of protonic pump inhibitors, if on one side can decrease aspirin-induced ulcers, on the other side reduces the efficacy of clopidogrel and [...]
-
The use of imaging techniques (US and CT) in case of acute abdominal pain no doubts gives help but with high costs, without thinking to radiation exposure caused by CT. Through a Dutch multicentric and prospective trial, 1021 adults with abdominal pain of a duration between 2 hours and 5 days have [...]
-
In order to evaluate the costs/benefits relation in bariatric surgery, this observational prospective trial has been performed on the data from 33 American surgical centers, examining the data of 4610 patients undergoing bariatric surgeries from 2005 to 2007. Average BMI was of 46.5 and performed [...]
-
According to previously performed trials, it was hypothesized that the discontinuation of a protonic pump inhibitor (PPI) can cause a rebound of acid hyper secretion, due to an increase, provoked by the PPI, of plasmatic gastrin, which, in its turn, stimulates gastric cells. When the PPI is [...]
-
Through a multicentric trial sponsored by pharmaceutical industry, 764 adults affected by bleeding gastric or duodenal ulcer have been treated with a high dose of intravenously infused esomeprazole or placebo. All patients presented endoscopic signs of recent bleeding and almost all of them had [...]