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Beside the important role of vitamin D in calcium homeostasis, from some small prospective trials, it seems that this substance also intervenes in the prevention of colorectal cancer: in fact, an inverse association between plasmatic levels of 25(OH)-D and the presence of colorectal cancer has been [...]
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Anti-androgen therapy, administered in the treatment of prostate cancer, implies the use of agonists of gonadotropin-releasing hormone (GnRH), like leuprolide and goserelin, beside oral anti-androgens, like flutamide and bicalutamide. Some recent trials have suggested the hypothesis that these [...]
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In a case-control trial, performed in Canada, the performance of colonoscopy has been associated with a decrease in the mortality for left colon cancer, but it has not influenced the mortality for right colon cancer. In another trial, some researchers in Germany have considered the problem, making [...]
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Splenectomy represents one of the therapeutical procedures used in some particular pathological conditions, like severe thrombocytopenia, hemolytic anemia, hematopoietic cancers, but it exposes the patient to a high risk of following infections. In order to quantify this risk, some researchers in [...]
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One of the most debated points concerning the treatment of prostate cancer is whether they should be managed immediately after diagnosis or they should undergo a watchful waiting. In a national cohort trial, some researchers have followed about 330 patients affected by prostate cancer for averagely [...]
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In 2002, the USPSTF (U.S. Preventive Services Task Force) recommended the performance of mammography as a screening in all women over 40 years of age to be repeated every 1-2 years. In an update in 2009, this recommendation has been reviewed according to the examination of risks and benefits, [...]
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After 1998, there has been a higher and higher intake of folic acid, because of some trials showing the importance of this substance in the prevention of neural tube defects, and following the fashion of these prescriptions the prophylactic indication has been spread also to the prevention of [...]
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If, on one side, it is true that colonoscopy can recognize a colorectal cancer, on the other side, it is all the same true that some cases of cancer are diagnosed late because the patient is tardily sent to colonoscopy. In order to verify the frequency of these delays, some researchers have [...]
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In women participating to the WHI (Women's Health Initiative) trial, treated with estrogen and progestin or placebo, substitutive hormone therapy (SHT) caused a higher incidence in cardiovascular diseases and breast cancer than placebo. Now, researchers present a further post hoc analysis, using [...]
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In the USA a strong promotion of the screening for prostate cancer and breast cancer has been made with an annual cost of 20 billion dollars only for these two cancers. In order to evaluate the efficacy and the opportunity of these two screenings it is necessary to keep in mind that, if the [...]