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In an international trial sponsored by pharmaceutical industry, 8556 women (averagely 67), responding to diagnostic criteria of osteoporosis, have been enrolled. For 5 years, they have been treated with placebo or with lasofoxifen, a selective modulator of estrogenic receptors, at the dosage of [...]
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Emergency contraception is based on levonorgestrel administration within 72 hours from a non-protected sexual intercourse. Ulipristal, a selective modulator of progestin receptors to be taken within 120 hours from the non-protected sexual intercourse, has been recently marketed with this purpose. [...]
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Post-menopause increases the risk of cardiovascular events, but which is the relation between this risk and the transitional period of menopause? And then, has woman’s age an influence or is it only hormone status to determine this risk? In a cohort, multi-ethnic trial, lasting 9 years, concerning [...]
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One of the problems tormenting women in perimenopausal period is the possibility to start an unwanted pregnancy. In order to evaluate which is the ovulation risk in this time interval, urine samples have been collected from 180 women (between 25 and 58 years of age) and the levels of FSH, of LH, of [...]
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Since assisted reproductive technology is spreading more and more, researchers have considered the problem of the relation between this technique and congenital malformations: the data from a perinatal registry of Ontario relative to 2005 and concerning women undergoing ovulation induction (298), [...]
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Papilloma virus (HPV) screening is performed in women over 30 years of age, since in young women HPV infections are often temporary and not doomed to cause cervical cancers. Besides, in women over 30, HPV vaccination can be a preventive weapon against cervical cancer, so a simulation trial [...]
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During pregnancy, the less drugs are used, the better is it. Among these, antibiotics are generally considered “necessary” and so their use is among the most frequent. Some researchers have analyzed the data from a national registry of congenital malformations to compare the use of antibiotics in [...]
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A woman under anticoagulation therapy can start a pregnancy. In that case, it is known that warfarin increases the risk of fetal defects or miscarriages, so new and safer anticoagulation agents are being researched. In general, a therapeutical shift towards low-molecular-weight heparins is made, so [...]
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We know from literature that the treatment of gestational diabetes is associated with better results as to perinatal complications, but it is not clear yet which is the relation between this form of diabetes and possible neonatal damages. So, 958 women with non-severe gestational diabetes have been [...]
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After the publication of the results from the WHI trial (Women's Health Initiative), in 2002, for estroprogestins, and in 2004 for estrogens alone, doubts and recommendations against these therapies have increased more and more: at enrolment, women were between 50 and 79 (averagely 63) and only [...]