Cardiology 

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  • Stroke risk in atrial fibrillation

    There is no doubt that a patient with atrial fibrillation (AF) is at higher risk of ischemic stroke, this being the reason for administering oral anticoagulation treatment (OAT). Since quantifying this risk and the actual benefit of OAT are still largely undetermined, many algorithms have been [...]


  • Risks of acetylsalicylic acid discontinuation in cardiovascular disease

    Although low dose acetylsalicylic acid (75-150 mg/day) is known to lower the risk of cardiovascular events in patients with stable cardiovascular disease, its use is often discontinued by patients because of its side effects or simple negligence. This case-control study, funded by the [...]


  • Kidney function and atrial fibrillation

    It is widely acknowledged that patients with chronic kidney disease are at higher risk for cardiovascular disease, but very little is known about its association with cardiac arrhythmia. To explore this association, investigators used the data from a large cohort study involving 10,328 patients [...]


  • NSAIDs and risk of atrial fibrillation

    A group of 2010 studies reported that NSAIDs are associated with an increased risk of atrial fibrillation (AF). To further investigate this, a study carried out in Denmark compared approximately 33,000 patients with a first diagnosis of AF with 326,000 matched controls. After customary adjustments [...]


  • Sudden death in women

    Coronary artery disease (CAD) can cause sudden and apparently inexplicable death, but a change in lifestyle can have a positive influence on CAD, thus reducing the risk of sudden death. Data from the Nurses' Health Study were used in 83,000 women (age at enrollment 30-55, no history of [...]


  • Nesiritide in acute decompensated heart failure (the ASCEND-HF Study)

    Nesiritide is a recombinant B-type natriuretic peptide which was approved by FDA in 2001 for the use in patients with acute decompensated heart failure, because it showed the ability to reduce pulmonary-capillary wedge pressure within few hours. However, in 2005 doubts were raised concerning its [...]


  • How to measure blood pressure

    What measurements should be used in the monitoring of blood pressure? The ones performed by patients at home, or the ones carried out in medical centers by physicians or nurses? The aim of this study was to determine the best measurement method and the optimal number of measurements for the correct [...]


  • NSAIDs and cardiovascular disease

    Following the publication in 2007 of guidelines highlighting the risk of using nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with cardiovascular disease, it is now acknowledged that long-term use of these drugs further increases the risk of ischemic events in these patients. However, [...]


  • Triglycerides and cardiovascular disease

    If on the one hand debate is still open on whether triglycerides have a role in promoting cardiovascular disease, on the other the level of fat in our diet keeps growing along with welfare, which translates into an increase in obesity and diabetes. Triglycerides levels are directly associated with [...]


  • Atrial fibrillatione and mortality in women

    After the Framingham study, which showed an increase in long-term mortality in patients – especially women – with new-onset atrial fibrillation (AF), later studies did not confirm this datum; hence, a group of investigators carried out a prospective study based on the participants of the Women's [...]


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