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A recent trial (NEJM 2010 Sep 19), involving patients whose asthma was not controlled by inhaled corticosteroids, showed that the addition of tiotropium was more effective than a higher dose of steroids, and was equivalent to a long-acting β2-agonist (LABAs).
Investigators have recently examined [...]
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In mild or moderate allergic rhinitis, endonasal steroids are advised as they are effective and with no side effects. Most patients affected by this disorder present however also ocular allergic manifestations, at the same time, so physicians often use oral anti-histamines prepared for conjunctival [...]
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Food allergy is not a wide problem, since it concerns averagely 1%-2% of the American population, and so it has not been studied in all its practical aspects, yet. With a trial sponsored by NIH, a review has been performed on the trials about food allergy published from 1988 to 2009, finding severe [...]
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Subcutaneous administration of desensitizing agents is the only shown way capable to change the natural history of allergy, but, because of a poor compliance and of the possibility of side effects, in Europe, sublingual administration has taken its place. But some questions still remain: do the two [...]
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A controversial theme, still being discussed, is the relationship between maternal diet during pregnancy, newborn diet and atopy development. Three trials have been performed in order to investigate on this relationship. In Holland, questionnaires given to 2516 families were collected and from [...]
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Mild asthma therapy generally implies the use of standard-dose inhaled corticosteroids, continued for an undefined time. Two new placebo-controlled, randomized trials, sponsored by pharmaceutical industry, involving each of them about 500 people with asthma, show that a decrease in dosages can be [...]
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In patients with persistent asthma, it is calculated an average lack of response in 30% of cases. In this NIH-sponsored study, researchers tried to establish whether the short-term response can, in some way, predict the response of prolonged administrations. 72 adults (between 18 and 55) with [...]
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Since non-ionic contrast media are used, anaphylactic reactions have greatly decreased, but in many radiology departments a preventive treatment is still advised. To verify the usefulness of these prescriptions, nine randomized trials were examined, involving 10.000 adults, in whom pre-treatment [...]