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Since there are on the market some anti-COX-2 molecules, their role in possible negative gastrointestinal effects remains under observation. In this case-control study, performed in England using a database of general population, 1.561 patient affected by complications of the upper gastrointestinal [...]
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Since treatment of the baby’s colics is always full of problems, some Italian authors have performed a not blind randomized study, treating 83 breast-fed babies presenting colics (more than three hours of daily cry for more than 3 days a week) through a probiotic (Lactobacillus Reuteri: 5 drops [...]
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It is not yet clear the need to use Endoscopic Retrograde Cholangio Pancreatography (ERCP) in patients affected by acute pancreatitis in the presence of gallstones. In this randomized trial, 103 patients with acute pancreatitis and evidence of biliary obstruction, common bile duct dilatation bigger [...]
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Even if ASA remains the most used antithrombotic drug, other therapies and the association of various drugs are increasing, even if data on their safety are still poor. In this case-control study, performed in Denmark, 1443 patients with severe bleedings of the gastrointestinal upper tract were [...]
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Gastroesophageal reflux disease (GERD) is a motility disorder caused by a temporary relaxation of the lower esophageal sphincter (LES), in general treated with antiacids in case of need, given that in the USA there is no drug with procinetic activity. Baclofen is an agonist of gamma-aminobutyric [...]
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The symptoms of a disorder do not always appear similarly in the various ages of life: some Italian researchers recorded the onset symptoms in 840 adult patients with endoscopic diagnosis of erosive oesophagitis. Patients affected by other diseases of the upper gastrointestinal tract (for example, [...]
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Statistics say that 40% of children develops diarrhea after the use of an antibiotic. In order to assess if probiotics can be used to repopulate intestinal flora and prevent antibiotic-related diarrhea, a meta-analysis was performed in Poland using data coming from six randomized trials on [...]
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The results of acidity inhibition in functional dyspepsia have been up to now conflicting. Now a new randomized study, sponsored by pharmaceutical industry, examines the efficacy of esomeprazole in 224 outpatients gone to their GP for non organic dyspepsia. All subjects agreed with the definition [...]
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According to some studies, bacterial gastroenteritis can evolve into a chronic form of irritable bowel. When the drinkable water of a little Canadian town was polluted in 2000 by industrial waste containing Campylobacter, Escherichia Coli and other pathogens, researchers had the possibility to [...]
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According to epidemiological studies, there is a relationship between gastric cancer and Helicobacter Pylori infection. In a randomized trial performed in China (but sponsored by U.S. National Cancer Institute) the effects of some interventions (eradication included) of precancerous lesions [...]