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One of the greatest problems and challenges for a physician is represented by the possibility to early find the presence of a malignant tumour according to some starting symptoms. Some English researchers have examined a wide database containing the data of general practitioners and assessed the [...]
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According to some animal and human observational trials the hypothesis was made that calcium and vitamin D administration can decrease breast cancer risk. Some researchers have prospectively assessed this possibility in 10.000 pre-menopausal women and 20.000 post-menopausal women enrolled in the [...]
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The report of malignant tumours and oncogenic viruses through organ transplantation are numerous, but the possibility of transmission through blood transfusion (which is only a transplantation of half-fluid tissue) has never been established. Some researchers have then examined the registries of [...]
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Researchers have spoken of the possibility of ASA to prevent colorectal cancer, even if two large randomized trials have denied this preventive effect after a 10-year follow-up. Now, they have the doubt that this period of observation has been too short, so long-term results of two English [...]
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A previous trial performed by Mayo Clinic had taken into consideration 1400 patients affected by monoclonal gammopathies of undetermined significance (MGUS) and had referred a risk of 8% of evolution into myeloma during the 15-year follow-up. Now, a trial performed in Spain describes the natural [...]
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In patients affected by cancer and undergoing chemotherapy, the severe anemia which often occurs can be treated with erythropoietin, even if this substance is associated with a decrease in survival. In order to face the problem, a trial was performed in Canada, randomizing patients with [...]
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The American College of Physicians has published a systematic review on risks and benefits of mammography performed between 40 and 49 years of age. Conclusions are:
• Mammography performed every 12-24 months decreases mortality for breast cancer of about 15%.
• There are indirect evidences that [...]
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Fortunately, acute lymphoblastic leukemia in childhood is a neoplasm with a favourable outcome after treatment, but we also know that survived children present a high risk to take a different neoplasm at the age of 15-20, even if this risk is not completely explained yet. This retrospective study [...]
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In some women, according to their anatomical breast characteristics, nuclear magnetic resonance (NMR) is a more sensitive examination than mammography in detecting tumours. In this multicentric trial the results obtained with contralateral breast NMR were examined in 969 women affected by recently [...]
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The U.S. Preventive Services Task Force (USPSTF) periodically releases updates on guidelines, always concluding with a recommendation classified in this way:
A The intervention is strongly recommended
B The intervention is recommended
C There are neither recommendations in favour nor [...]