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In non-scientific publications (New York Times) the news that finasteride would be capable to prevent prostate cancer has recently appeared, so it is necessary to know which really is the present situation on this specific subject. In 2003, the results of the Prostate Cancer Prevention Trial study [...]
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Predisposition to breast cancer is documented by the presence of BRCA1 and BRCA2 mutations, and women having them must be accurately monitored in order to be able to perform an early diagnosis. For this reason, also magnetic resonance imaging (MRI) is associated with the traditional mammography, [...]
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The slow climb of the prescriptive supremacy in breast cancer by aromatase inhibitors compared to the “old” tamoxifen continues: three further reports are added confirming the validity of their use as adjuvant drugs.
In the MA.17 randomized trial, 5169 post-menopausal women with breast cancer [...]
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It is not clear yet which is the best treatment of localized prostate cancer, so some researchers have examined 473 observational trials and 18 RCT in which biochemical and clinical results obtained in patients with this cancer were referred. Only one randomized trial concerned males in whom cancer [...]
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The American Cancer Society, the American College of Radiology and the Multi-Society Task Force on Colorectal Cancer (including various gastroenterological study groups) have realized new guidelines to establish the risk of colorectal neoplasms, referring to documents previously published during [...]
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The association between obesity and some kinds of cancer is well known, but what is unknown is the risk represented by obesity in less common cancers and whether there are differences between the two genders in this. A meta-analysis was performed on 221 prospective trials in which basal BMI and [...]
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We know that ovarian cancer increases with age increasing and that the use of oral contraceptives decreases the risk of its onset. But how long is the benefit after contraceptive interruption? In order to answer this question, data from 45 observational trials on ovarian cancer risk factors were [...]
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In older women with breast cancer the therapeutical decision is more complex than in younger women: with age increasing, comorbidities increase, life expectancy is lower, but cancer aggressiveness is generally less marked. Some Italian researchers have followed 354 women between 70 and 92, affected [...]
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In women affected by breast cancer aromatase inhibitors are more and more used (anastrozole, letrozole and exemestane). In the ATAC trial (Arimidex, Tamoxifen, Alone or in Combination Trialists' Group) the use of anastrozole and tamoxifen was compared in post-menopausal women affected by [...]
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Compared to thin subjects, obese people present lower PSA levels, without prostate cancer, while among prostate cancer carriers, obesity is associated with poorer results. Associating these two observations, some researchers have studied PSA levels in 13,634 subjects (average age 60 years old) [...]