Psichiatria 

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  • SSRIs in pregnancy and risk of autism

    There are several risks involved in taking SSRIs antidepressants during pregnancy (the most frequent being abortion, congenital heart disease, pulmonary hypertension). This case-control study examined the effects of exposure to SSRIs in 298 children with autism spectrum disorders (ASDs) and 1,507 [...]


  • Venlafaxine in Generalized Anxiety Disorder

    The generalized anxiety disorder (GAD) is a chronic disease needing long-term treatments. In order to verify the obtainable benefit with a 6-month and a 12-month therapy through long-term-release venlafaxine, 268 subjects with a diagnosis of GAD have been treated through an open-label study: after [...]


  • How to Interrupt Antidepressants

    When we speak of sudden interruption of treatment, we refer to a period of 1-7 days, while gradual interruption implies the use of a drug at reduced doses for at least 14 days. In order to verify the results obtainable with a sudden to gradual interruption of antidepressants, some Italian [...]


  • Depression Screening

    The USPSTF (U.S. Preventive Services Task Force) has published new guidelines concerning depression screening in adults, after having performed a systematic review on the available evidence. The results, compared to the previous edition in 2002, is that screening is now advised only when there is [...]


  • Preventing Depression in Adolescents

    The presence of depression in parents increases of 2-3 times the risk of depression in adolescents, so with this multicentric trial relative to cognitive-behavioural therapy (CBT), some researchers have en-rolled 316 adolescents (between 13 and 17) with one of the following characteristics: the [...]


  • Depression Screening Among Teenagers

    American data show a prevalence of major depressive disorders (MDD) of 3% in children and of 6% in teenagers, but, in spite of this, the U.S. Preventive Services Task Force (USPSTF) didn’t advice, in 2002, the screening for this disease in childhood and teenage. Now, the USPSTF changes its mind and [...]


  • Antidepressants in Fibromyalgia

    In the treatment of fibromyalgia (a syndrome which is still difficult to understand and solve) antidepressants are used, even if the patient does not present any symptoms or typical signs of a depressive episode. The extent of the obtainable benefit is however irregular, so some German researchers [...]


  • Second-Generation Antidepressants

    The American College of Physicians (ACP) issued its guidelines for the use of second-generation antidepressants in depressed patients. Such recommendations are based on a review of 203 trials concerning 12 antidepressants, including selective serotonin reuptake inhibitors (SSRIs) and [...]


  • Prevention of Depression after Stroke

    About 40% of patients undergoing stroke experience, after the vascular accident, a more or less severe depression, but such to further worsen their quality of life. Antidepressants used in this occasion have given contrasting results, so a multicentric trial was performed involving 176 patients [...]


  • Antipsychotics and Mortality

    In spite of the wide use of antipsychotics in patients affected by dementia, researchers speak more and more often of an association between these drugs and an increase in mortality, so a retrospective trial was performed to compare mortality rates in patients with dementia treated with [...]


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