Medicina generale 

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  • Vitamin D and Mortality

    Supporters of the usefulness of vitamin D supplementation affirm that, beside improving bone metabolism, this vitamin is capable to produce beneficial effects also on other organs and systems, preventing the onset of various dysfunctions. For this reason, newer and newer trial are performed with [...]


  • Waist Circumference and Mortality

    Waist circumference, as an expression of central adiposity, is associated with insulin resistance, with type 2 diabetes, with dyslipidemia and with coronary artery diseases, with the result that there is an evident relation between waist measure and life expectation. This relation is independent [...]


  • Treatment of Resistant Pediculosis

    The first-choice treatment in case of pediculosis is the use of a permethrin-based cream or a pyrethrum-based lotion. With this international randomized, double-blinded trial, two second-choice treatments have been compared in patients and cohabitants infested by lice and recently unsuccessfully [...]


  • Transdermal Nicotine in Smoke Cessation

    In subjects with smoke habit wanting to quit their addiction, a treatment of at least 8 weeks, based on transdermal nicotine is advised. To verify its efficacy in even longer periods, a randomized trial has been performed on 568 long-time smokers, treated for 8 weeks with plasters containing 21 mg [...]


  • Gabapentin and Nortriptyline in Neuropathic Pain

    Gabapentin and nortriptyline are first-use drugs in neuropathic pain, but they present unpleasant side effects according to the used dose and their efficacy is limited. In this trial, it was evaluated whether drugs can be more effective in combined therapy, since their mechanism of action is [...]


  • Screening on Smoke Habit

    In 2003, the U.S. Preventive Services Task Force (USPSTF) recommended physicians to make for their own patients a counseling concerning the damages deriving from smoke habit; in 2008, the available evidences have been again examined and the indication to the screening on smoke habit has had a new [...]


  • Physical Exercise and Mortality in Middle Age

    Is it really healthy to do physical exercise? In Sweden, a prospective population trial was performed, examining the consequences of physical exercise and smoke cessation on 2205 males (average age 50 at the beginning of the trial, in 1970-1973). After a follow-up of 35 years, the mortality rates [...]


  • Lifestyle and Death Risk

    A famous prospective trial performed in the ‘80s concerned 77,782 US nurses between 34 and 59, without cardiovascular diseases and cancers, who periodically completed some questionnaires relative to lifestyle, in order to assess possible associations between measurable factors and these two [...]


  • Muscular Strength And Long-Term Mortality

    There have been, in the past, some trials identifying an inversely proportional relation between muscular strength and life expectancy, but these trials were invalidated by methodological faults (the ways in which muscular strength had been measured varied, follow-up was too short, also old [...]


  • Placebo Effect

    The placebo effect is a widely shown phenomenon, but on whose mechanism there is not an absolute clearness yet, so some researchers have made 262 adults affected by irritable bowel syndrome undergoing three different therapeutical regimens: clinical examination and simple observation, placebo [...]


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