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A number of studies has shown that treatments involving excessive doses of statins may be associated with patients developing insulin resistance, resulting in higher risk of developing type 2 diabetes. To examine this possibility, investigators carried out a meta-analysis of 5 randomized statin [...]
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Increased physical activity and dietary management is universally recommended in the initial treatment of type 2 diabetes. Yet, if these most-important treatments are started at diagnosis, what effects do they produce in the long run? To assess this issue, a recent British study randomized 593 [...]
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When diabetes mellitus is diagnosed in a patient showing no symptoms, what is the best therapeutic approach? In an effort to answer this question, a group of British, Danish and Dutch investigators randomized 343 general practices to treat, either with routine care or intensive treatment, 3,057 [...]
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If on the one hand type 2 diabetes is associated with higher bone density, paradoxically on the other hand it has increased fracture risk, which is difficult to assess using current methods (such as FRAX scoring or measuring bone mineral density [BMD] using DEXA scanning). In an effort to address [...]
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In type 2 diabetics, aerobic physical exercise and resistance exercises are recommended, but we know little on the usefulness of both practices and on the possible advantage compared to the individual action. With a randomized, case-control study, 262 sedentary diabetics (averagely 56 years of age; [...]
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Not all patients affected by type 1 diabetes develop microvascular and macrovascular complications, and an investigation performed at the Boston's Joslin Diabetes Center on 251 diabetics followed for about 50 years demonstrates it: in spite of the long period of time, many of them have presented no [...]
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In the randomized study called ACCORD, 10,000 type 2 old diabetics have been treated in order to reach an intensive control of glycemia (HbA1c taken below 6%) or according to traditional therapies (HbA1c between 7.0% and 7.9%). According to previously published results, it was seen that the [...]
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The condition of impaired glucose tolerance is a predisposing factor for the subsequent onset of a real diabetes mellitus. Can this progression be slowed down or even eliminated through the assumption of pioglitazone? In order to verify this hypothesis, a study has been performed in Texas on 602 [...]
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We think that normally, in hospitalized patients, there is hyperglycemia in 40% of cases, and, since hyperglycemia is associated with an increase in morbidity and mortality, researchers have wondered whether an intensive glycemic control can improve the prognosis of patients hospitalized for any [...]
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An association has been remarked between intestinal infections caused by enteroviruses and following development of type 1 diabetes, so now a meta-analysis has been performed to verify this statement, using molecular tests to diagnose the viral infection. Most examined patients were affected by [...]