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What is the best treatment approach to avoid the risk of recurrence after a first event of deep vein thrombosis (DVT)? Could the length of anticoagulation become a helpful parameter in order to reduce this risk? In an effort to answer this question, investigators carried out a meta-analysis of 7 [...]
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Statistics show that 18% of women in the U.S. are smokers, and smoking remains a risk factor for peripheral artery disease (PAD) in women, although possibly developing in different ways than in men. To better understand this aspect, a study analyzed the data of 40,000 women with no cardiovascular [...]
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In 1960, this rare syndrome (SCLS: Systemic Capillary Leak Syndrome), on which 130 cases all over the world have now been reported, was first described. Acute attacks develop in a few hours with a severe hypotension, edemas, hemoconcentration and hyponchia. Some researchers in Paris have recently [...]
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When an episode of venous thromboembolism occurs, caused by a non-permanent risk factor, the duration of standard anticoagulation treatment is of about 3 months, and the consequent possibility of a new thromboembolic episode is low, in agreement with possibly present risk factors (surgery, [...]
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Some X-factor inhibitors, which have the advantage to be given orally in a fixed dose and don’t require any coagulation monitoring (differently from warfarin) are under study. Some examples of these drugs are rivaroxaban and apixaban. In a double-blind trial sponsored by pharmaceutical industry, [...]
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There are not clear data yet on the incidence and the risk factors of a post-thrombotic syndrome after an episode of deep venous thrombosis (DVT). Through a prospective cohort trial, 387 patients with DVT in eight hospitals in Canada have been treated with heparin followed by warfarin and monitored [...]
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The American Academy of Family Physicians and the American College of Physicians, according to published evidences, issued some guidelines on the diagnosis of venous thromboembolism in general practice. In this document, the following behavioural advises are given:
1. Use validated predictive [...]
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The standard treatment of Kawasaki disease uses intravenous immunoglobulins associated with ASA, while favourable results obtained with cortisone in complicated forms of the disease have driven some clinicians to add these substances to the basic therapy of the disease. In an American [...]
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According to some studies on animals it seems that the renin-angiotensin system comes into play in favouring the formation of abdominal aortic aneurysms (AAA); consequently, the use of ACE-inhibitors could be able to prevent their formation and progression. To verify this hypothesis in humans, in [...]
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In the last decade, thromboembolism therapy has seen the shift from the use of unfractionated heparin administered by endovenous route and low-molecular-weight heparin injected under the skin, presenting the advantage of being injected also at home and of not having the need of a coagulation [...]