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Although low dose acetylsalicylic acid (75-150 mg/day) is known to lower the risk of cardiovascular events in patients with stable cardiovascular disease, its use is often discontinued by patients because of its side effects or simple negligence. This case-control study, funded by the [...]
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It is traditional knowledge that patients should undergo a lumbar puncture to ascertain subarachnoid haemorrhage, independently of the results from CT. A recent prospective study investigated 3,132 neurological patients aged over 15 years, with third generation head CT scanning to evaluate [...]
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Lung function in patients with asthma is measured using spirometry, and it is known that placebo can influence the clinical result, sometimes even remarkably. Addressing this point, a study was carried out on 46 patients with asthma: each patient was treated, in different days, with either an [...]
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The 2009 USPSTF (U.S. Preventive Services Task Force) guidelines have reopened the question of mass population mammographic screening, especially after the results of a Swedish study in which 133,000 women with no history of breast cancer were randomized to undergo either screening, once every 2 [...]
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Tumor necrosis factor (TNF) inhibitors increase the risk of infection in patients with rheumatoid arthritis (RA). In order to quantify this risk, investigators in Japan compared the records from 646 patients treated with either etanercept or infliximab and 498 treated with nonbiological drugs.; [...]
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It is widely acknowledged that patients with chronic kidney disease are at higher risk for cardiovascular disease, but very little is known about its association with cardiac arrhythmia. To explore this association, investigators used the data from a large cohort study involving 10,328 patients [...]
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A number of studies has shown that treatments involving excessive doses of statins may be associated with patients developing insulin resistance, resulting in higher risk of developing type 2 diabetes. To examine this possibility, investigators carried out a meta-analysis of 5 randomized statin [...]
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What is the best treatment approach to avoid the risk of recurrence after a first event of deep vein thrombosis (DVT)? Could the length of anticoagulation become a helpful parameter in order to reduce this risk? In an effort to answer this question, investigators carried out a meta-analysis of 7 [...]
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A group of 2010 studies reported that NSAIDs are associated with an increased risk of atrial fibrillation (AF). To further investigate this, a study carried out in Denmark compared approximately 33,000 patients with a first diagnosis of AF with 326,000 matched controls. After customary adjustments [...]
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Coronary artery disease (CAD) can cause sudden and apparently inexplicable death, but a change in lifestyle can have a positive influence on CAD, thus reducing the risk of sudden death. Data from the Nurses' Health Study were used in 83,000 women (age at enrollment 30-55, no history of [...]