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<title>Paroxetine and Tamoxifen</title>
<link>http://mn.medsurfnews.com/contents/en/5625/display/paroxetine-and-tamoxifen.aspx</link>
<pubDate>Mon, 9 Aug 2010 12:00:00 +0200</pubDate>
<category>Pharmacology</category>
<description><![CDATA[Tamoxifen does not act directly, but it must be transformed in its active metabolite, endoxifen, by 2D6 isoenzyme of P450 cytochrome. In women affected by early-stage breast cancer sensitive to estrogenic receptors, tamoxifen decreases the risk of relapses of about 50% and the risk of death for [...]]]></description>

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<title>Transdermal Nicotine in Smoke Cessation</title>
<link>http://mn.medsurfnews.com/contents/en/5626/display/transdermal-nicotine-in-smoke-cessation.aspx</link>
<pubDate>Mon, 9 Aug 2010 12:00:00 +0200</pubDate>
<category>General medicine</category>
<description><![CDATA[In subjects with smoke habit wanting to quit their addiction, a treatment of at least 8 weeks, based on transdermal nicotine is advised. To verify its efficacy in even longer periods, a randomized trial has been performed on 568 long-time smokers, treated for 8 weeks with plasters containing 21 mg [...]]]></description>

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<title>Lithium and Valproic Acid in Bipolar Disorders</title>
<link>http://mn.medsurfnews.com/contents/en/5627/display/lithium-and-valproic-acid-in-bipolar-disorders.aspx</link>
<pubDate>Mon, 9 Aug 2010 12:00:00 +0200</pubDate>
<category>Pharmacology</category>
<description><![CDATA[In the prevention of relapses of bipolar disorders, lithium carbonate, sodium valproate or both drugs are used, even if a direct comparison between monotherapies and the combined therapy has not been made yet. In this international trial, 459 adults affected by bipolar disorders in remission phase [...]]]></description>

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<title>Opioids and their Risks</title>
<link>http://mn.medsurfnews.com/contents/en/5640/display/opioids-and-their-risks.aspx</link>
<pubDate>Mon, 9 Aug 2010 12:00:00 +0200</pubDate>
<category>Palliative Care</category>
<description><![CDATA[The use of opioids trying to control chronic pain is more and more increasing, but, as a consequence, cases of overdose are more and more frequent. Since the risks of overdose have not been described in patients with chronic pain, yet, some researchers in the State of Washington have examined 9940 [...]]]></description>

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